Publications from Gastroenterology and Hepatology

Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease

Fridén, Michael; Rosqvist, Fredrik; Ahlström, Håkan; Niessen, Heiko G. et al.

Part of Frontiers in Medicine, 2022.

Article in journal

DOI for Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease Download full text (pdf) of Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease

Automated data extraction of electronic medical records: Validity of data mining to construct research databases for eligibility in gastroenterological clinical trials

Joseph, Nora; Lindblad, Ida; Zaker, Sara; Elfversson, Sharareh et al.

Part of Upsala Journal of Medical Sciences, 2022.

Article in journal

DOI for Automated data extraction of electronic medical records: Validity of data mining to construct research databases for eligibility in gastroenterological clinical trials Download full text (pdf) of Automated data extraction of electronic medical records: Validity of data mining to construct research databases for eligibility in gastroenterological clinical trials

Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans

Rosqvist, Fredrik; Fridén, Michael; Vessby, Johan; Hockings, Paul et al.

Part of Clinical Nutrition, p. 805-809, 2022.

Article in journal

DOI for Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans Download full text (pdf) of Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans

Measurement of Serum IgG Anti-Integrin alpha v beta 6 Autoantibodies Is a Promising Tool in the Diagnosis of Ulcerative Colitis

Rydell, Niclas; Ekoff, Helena; Hellström, Per M.; Movérare, Robert

Part of Journal of Clinical Medicine, 2022.

Article in journal

DOI for Measurement of Serum IgG Anti-Integrin alpha v beta 6 Autoantibodies Is a Promising Tool in the Diagnosis of Ulcerative Colitis Download full text (pdf) of Measurement of Serum IgG Anti-Integrin alpha v beta 6 Autoantibodies Is a Promising Tool in the Diagnosis of Ulcerative Colitis

High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium.

van Rijn, Jorik M; Eriksson, Jens; Grüttner, Jana; Sundbom, Magnus et al.

Part of mBio, 2022.

Article in journal

DOI for High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium. Download full text (pdf) of High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium.

AGPAT1 as a Novel Colonic Biomarker for Discriminating Between Ulcerative Colitis With and Without Primary Sclerosing Cholangitis

Vessby, Johan; Wisniewski, Jacek R.; Lindskog, Cecilia; Eriksson, Niclas et al.

Part of Clinical and Translational Gastroenterology, 2022.

Article in journal

DOI for AGPAT1 as a Novel Colonic Biomarker for Discriminating Between Ulcerative Colitis With and Without Primary Sclerosing Cholangitis

An Increasing Incidence of Upper Gastrointestinal Disorders Over 23 Years: A Prospective Population-Based Study in Sweden

Andreasson, Anna; Talley, Nicholas J.; Walker, Marjorie M.; Jones, Michael P. et al.

Part of American Journal of Gastroenterology, p. 210-213, 2021.

Article in journal

DOI for An Increasing Incidence of Upper Gastrointestinal Disorders Over 23 Years: A Prospective Population-Based Study in Sweden

Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies

Dahlgren, David; Sjöblom, Markus; Hellström, Per M.; Lennernäs, Hans

Part of Frontiers in Pharmacology, 2021.

Article, review/survey

DOI for Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies Download full text (pdf) of Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies

Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability

Dahlgren, David; Venczel, M.; Ridoux, J. -P; Skjöld, C. et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 240-251, 2021.

Article in journal

DOI for Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability Download full text (pdf) of Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability

Extrahepatic autoimmune diseases in primary biliary cholangitis: Prevalence and significance for clinical presentation and disease outcome

Efe, Cumali; Torgutalp, Murat; Henriksson, Ida; Alalkim, Fatema et al.

Part of Journal of Gastroenterology and Hepatology, p. 936-942, 2021.

Article in journal

DOI for Extrahepatic autoimmune diseases in primary biliary cholangitis: Prevalence and significance for clinical presentation and disease outcome

Gastrointestinal Physiology Before and After Duodenal Switch with Comparisons to Unoperated Lean Controls: Novel Use of the SmartPill Wireless Motility Capsule

Elias, Khalid; Hellström, Per M.; Webb, Dominic-Luc; Sundbom, Magnus

Part of Obesity Surgery, p. 3483-3489, 2021.

Article in journal

DOI for Gastrointestinal Physiology Before and After Duodenal Switch with Comparisons to Unoperated Lean Controls: Novel Use of the SmartPill Wireless Motility Capsule Download full text (pdf) of Gastrointestinal Physiology Before and After Duodenal Switch with Comparisons to Unoperated Lean Controls: Novel Use of the SmartPill Wireless Motility Capsule

Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids

Geiser, Petra; Di Martino, Maria Letizia; Samperio Ventayol, Pilar; Eriksson, Jens et al.

Part of mBio, 2021.

Article in journal

DOI for Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids Download full text (pdf) of Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids

Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose.

Grudén, Stefan; Forslund, Anders; Alderborn, Göran; Söderhäll, Arvid et al.

Part of Clinical Pharmacology in Drug Development, p. 1242-1247, 2021.

Article in journal

DOI for Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose. Download full text (pdf) of Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose.

Morbidity, risk of cancer and mortality in 3645 HFE mutations carriers

Hagström, Hannes; Ndegwa, Nelson; Jalmeus, Molly; Ekstedt, Mattias et al.

Part of Liver international (Print), p. 545-553, 2021.

Article in journal

DOI for Morbidity, risk of cancer and mortality in 3645 HFE mutations carriers Download full text (pdf) of Morbidity, risk of cancer and mortality in 3645 HFE mutations carriers

Localized IgG4-related disease manifested on the tongue: a case report

Hashemi, Helya; Thor, Andreas; Hellbacher, Erik; Carlson, Marie et al.

Part of Upsala Journal of Medical Sciences, 2021.

Article in journal

DOI for Localized IgG4-related disease manifested on the tongue: a case report Download full text (pdf) of Localized IgG4-related disease manifested on the tongue: a case report

Gastrointestinal bleeding in patients with Helicobacter pylori and dual platelet inhibition after myocardial infarction: Comment

Hellström, Per M.; Benno, Peter; Malfertheiner, Peter

Part of The Lancet Gastroenterology & Hepatology, p. 684-685, 2021.

Article in journal

DOI for Gastrointestinal bleeding in patients with Helicobacter pylori and dual platelet inhibition after myocardial infarction: Comment

A hypocaloric diet rich in high fiber rye foods causes greater reduction in body weight and body fat than a diet rich in refined wheat: A parallel randomized controlled trial in adults with overweight and obesity (the RyeWeight study)

Iversen, Kia Nøhr; Carlsson, Frida; Andersson, Agneta; Michaëlsson, Karl et al.

Part of Clinical Nutrition, p. 155-169, 2021.

Article in journal

DOI for A hypocaloric diet rich in high fiber rye foods causes greater reduction in body weight and body fat than a diet rich in refined wheat: A parallel randomized controlled trial in adults with overweight and obesity (the RyeWeight study) Download full text (pdf) of A hypocaloric diet rich in high fiber rye foods causes greater reduction in body weight and body fat than a diet rich in refined wheat: A parallel randomized controlled trial in adults with overweight and obesity (the RyeWeight study)

A pilot study of golexanolone, a new GABA-A receptor-modulating steroid antagonist, in patients with covert hepatic encephalopathy

Montagnese, Sara; Lauridsen, Mette; Vilstrup, Hendrik; Zarantonello, Lisa et al.

Part of Journal of Hepatology, p. 98-107, 2021.

Article in journal

DOI for A pilot study of golexanolone, a new GABA-A receptor-modulating steroid antagonist, in patients with covert hepatic encephalopathy Download full text (pdf) of A pilot study of golexanolone, a new GABA-A receptor-modulating steroid antagonist, in patients with covert hepatic encephalopathy

Fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs), but not gluten, elicit modest symptoms of irritable bowel syndrome: a double-blind, placebo-controlled, randomized three-way crossover trial

Nordin, Elise; Brunius, Carl; Landberg, Rikard; Hellström, Per M.

Part of American Journal of Clinical Nutrition, p. 344-352, 2021.

Article in journal

DOI for Fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs), but not gluten, elicit modest symptoms of irritable bowel syndrome: a double-blind, placebo-controlled, randomized three-way crossover trial Download full text (pdf) of Fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs), but not gluten, elicit modest symptoms of irritable bowel syndrome: a double-blind, placebo-controlled, randomized three-way crossover trial

Effects of Helicobacter pylori on Levodopa Pharmacokinetics

Nyholm, Dag; Hellström, Per M.

Part of Journal of Parkinson's Disease, p. 61-69, 2021.

Article, review/survey

DOI for Effects of Helicobacter pylori on Levodopa Pharmacokinetics Download full text (pdf) of Effects of Helicobacter pylori on Levodopa Pharmacokinetics

Treatment and outcome of ulcerative colitis during the first 10 years after diagnosis in a prospectively followed population-based cohort

Rönnblom, Anders; Karlbom, Urban

Part of Scandinavian Journal of Gastroenterology, p. 403-409, 2021.

Article in journal

DOI for Treatment and outcome of ulcerative colitis during the first 10 years after diagnosis in a prospectively followed population-based cohort

Complications and adverse effects related to surgical and medical treatment in patients with inflammatory bowel disease in a prospectively recruited population-based cohort

Rönnblom, Anders; Ljunggren, Östen; Karlbom, Urban

Part of Scandinavian Journal of Gastroenterology, p. 1296-1303, 2021.

Article in journal

DOI for Complications and adverse effects related to surgical and medical treatment in patients with inflammatory bowel disease in a prospectively recruited population-based cohort

Elevated gaseous luminal nitric oxide and circulating IL-8 as features of Helicobacter pylori-induced gastric inflammation

Saaed, Hiwa K.; Chiggiato, Lisa; Webb, Dominic-Luc; Rehnberg, Ann-Sofie et al.

Part of Upsala Journal of Medical Sciences, 2021.

Article in journal

DOI for Elevated gaseous luminal nitric oxide and circulating IL-8 as features of Helicobacter pylori-induced gastric inflammation Download full text (pdf) of Elevated gaseous luminal nitric oxide and circulating IL-8 as features of Helicobacter pylori-induced gastric inflammation

Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers

Samperio Ventayol, Pilar; Geiser, Petra; Di Martino, Maria Letizia; Florbrant, Alexandra et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2021.

Article in journal

DOI for Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers Download full text (pdf) of Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers

Peritumoral portal enhancement during transarterial chemoembolization: a potential prognostic factor for patients with hepatocellular carcinoma.

Sennefelt Nyman, Sofi; Dimopoulou, Angeliki; Johnson, Ulf; Rorsman, Fredrik et al.

Part of Acta Radiologica, 2021.

Article in journal

DOI for Peritumoral portal enhancement during transarterial chemoembolization: a potential prognostic factor for patients with hepatocellular carcinoma. Download full text (pdf) of Peritumoral portal enhancement during transarterial chemoembolization: a potential prognostic factor for patients with hepatocellular carcinoma.

A New Hybrid Concept, Combining Lectures and Case-Seminars, Resulted in Superior Ratings from Both Undergraduate Medical Students and Teachers

Sundbom, Magnus; Hellström, Per; Graf, Wilhelm

Part of Advances in Medical Education and Practice, p. 597-605, 2021.

Article in journal

DOI for A New Hybrid Concept, Combining Lectures and Case-Seminars, Resulted in Superior Ratings from Both Undergraduate Medical Students and Teachers Download full text (pdf) of A New Hybrid Concept, Combining Lectures and Case-Seminars, Resulted in Superior Ratings from Both Undergraduate Medical Students and Teachers

Role of smoking in functional dyspepsia and irritable bowel syndrome: three random population-based studies

Talley, Nicholas J.; Powell, Nicholas; Walker, Marjorie M.; Jones, Mike P. et al.

Part of Alimentary Pharmacology and Therapeutics, p. 32-42, 2021.

Article in journal

DOI for Role of smoking in functional dyspepsia and irritable bowel syndrome: three random population-based studies

Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

Alanazi, Sultan; Grujic, Mirjana; Lampinen, Maria; Rollman, Ola et al.

Part of International Journal of Molecular Sciences, 2020.

Article in journal

DOI for Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA Download full text (pdf) of Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol

Dahlgren, David; Cano-Cebrian, Maria-Jose; Hellström, Per M.; Wanders, Alkwin et al.

Part of International Journal of Molecular Sciences, 2020.

Article in journal

DOI for Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol Download full text (pdf) of Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol

Placement of a transjugular intrahepatic portosystemic shunt in addition to recanalization of acute and chronic portomesenteric vein occlusions: a retrospective evaluation

Ebeling Barbier, Charlotte; Rorsman, Fredrik; Eriksson, Lars-Gunnar; Sangfelt, Per et al.

Part of Acta Radiologica, Supplement, 2020.

Article in journal

DOI for Placement of a transjugular intrahepatic portosystemic shunt in addition to recanalization of acute and chronic portomesenteric vein occlusions: a retrospective evaluation Download full text (pdf) of Placement of a transjugular intrahepatic portosystemic shunt in addition to recanalization of acute and chronic portomesenteric vein occlusions: a retrospective evaluation

Effects of whole-grain wheat, rye, and lignan supplementation on cardiometabolic risk factors in men with metabolic syndrome: a randomized crossover trial

Eriksen, Anne K.; Brunius, Carl; Mazidi, Mohsen; Hellström, Per M. et al.

Part of American Journal of Clinical Nutrition, p. 864-876, 2020.

Article in journal

DOI for Effects of whole-grain wheat, rye, and lignan supplementation on cardiometabolic risk factors in men with metabolic syndrome: a randomized crossover trial

Gastroparesis versus dyspepsia by intragastric meal distribution: new diagnostics and definitions ahead

Gryback, Per; Jacobsson, Hans; Neuger, Lucyna; Hellström, Per M.

Part of Scandinavian Journal of Gastroenterology, p. 251-255, 2020.

Article in journal

DOI for Gastroparesis versus dyspepsia by intragastric meal distribution: new diagnostics and definitions ahead

Genetic and shared environmental risk factors do not lead to eosinophil activation in healthy twins of IBD patients

Halfvarson, Jonas; Lundström, Maria Ling; Lampinen, Maria; Schoultz, Ida et al.

Part of Scandinavian Journal of Gastroenterology, p. 1163-1170, 2020.

Article in journal

DOI for Genetic and shared environmental risk factors do not lead to eosinophil activation in healthy twins of IBD patients

Effects of Tumor Necrosis Factor Antagonists in Patients With Primary Sclerosing Cholangitis

Hedin, Charlotte Rose Hawkey; Sado, Gina; Ndegwa, Nelson; Lytvyak, Ellina et al.

Part of Clinical Gastroenterology and Hepatology, p. 2295-2304.e2, 2020.

Article in journal

DOI for Effects of Tumor Necrosis Factor Antagonists in Patients With Primary Sclerosing Cholangitis

Liver cirrhosis turns life into an unpredictable roller-coaster: A qualitative interview study

Hjorth, Maria; Svanberg, Anncarin; Sjöberg, Daniel; Rorsman, Fredrik et al.

Part of Journal of Clinical Nursing, p. 4532-4543, 2020.

Article in journal

DOI for Liver cirrhosis turns life into an unpredictable roller-coaster: A qualitative interview study Download full text (pdf) of Liver cirrhosis turns life into an unpredictable roller-coaster: A qualitative interview study

Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity

Holmbäck, Ulf; Forslund, Anders; Gruden, Stefan; Alderborn, Göran et al.

Part of Obesity Science & Practice, p. 313-323, 2020.

Article in journal

DOI for Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity Download full text (pdf) of Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity

Season does not have a deleterious effect on proportions of stallion seminal plasma proteins

Johannisson, Anders; Al-Essawe, Essraa M.; Al-Saffar, Ahmad; Karkehabadi, Saeid et al.

Part of Journal of reproduction and development, p. 215-221, 2020.

Article in journal

DOI for Season does not have a deleterious effect on proportions of stallion seminal plasma proteins Download full text (pdf) of Season does not have a deleterious effect on proportions of stallion seminal plasma proteins

Clinical course of Crohn's disease in a population-based cohort in Uppsala County followed for 10 years

Rönnblom, Anders; Karlbom, Urban

Part of Scandinavian Journal of Gastroenterology, p. 1301-1307, 2020.

Article in journal

DOI for Clinical course of Crohn's disease in a population-based cohort in Uppsala County followed for 10 years

Acute severe attacks of ulcerative colitis in a population-based cohort: epidemiology, treatment and outcome

Rönnblom, Anders; Karlbom, Urban

Part of Scandinavian Journal of Gastroenterology, p. 555-559, 2020.

Article in journal

DOI for Acute severe attacks of ulcerative colitis in a population-based cohort: epidemiology, treatment and outcome

International consensus on the diagnosis and management of dumping syndrome

Scarpellini, Emidio; Arts, Joris; Karamanolis, George; Laurenius, Anna et al.

Part of Nature Reviews Endocrinology, p. 448-466, 2020.

Article in journal

DOI for International consensus on the diagnosis and management of dumping syndrome Download full text (pdf) of International consensus on the diagnosis and management of dumping syndrome

The use of ICD codes to identify IBD subtypes and phenotypes of the Montreal classification in the Swedish National Patient Register

Shrestha, Sarita; Olén, Ola; Eriksson, Carl; Everhov, Åsa H. et al.

Part of Scandinavian Journal of Gastroenterology, p. 430-435, 2020.

Article in journal

DOI for The use of ICD codes to identify IBD subtypes and phenotypes of the Montreal classification in the Swedish National Patient Register Download full text (pdf) of The use of ICD codes to identify IBD subtypes and phenotypes of the Montreal classification in the Swedish National Patient Register

A cross-sectional study of gastrointestinal symptoms, depressive symptoms and trait anxiety in young adults

Söderquist, Fanny; Syk, Mikaela; Just, David; Novicic, Zorana Kurbalija et al.

Part of BMC Psychiatry, 2020.

Article in journal

DOI for A cross-sectional study of gastrointestinal symptoms, depressive symptoms and trait anxiety in young adults Download full text (pdf) of A cross-sectional study of gastrointestinal symptoms, depressive symptoms and trait anxiety in young adults

Diagnostic accuracy of a quantitative faecal immunochemical test vs. symptoms suspected for colorectal cancer in patients referred for colonoscopy

Tsapournas, Georgios; Hellström, Per M.; Cao, Yang; Olsson, Louise I.

Part of Scandinavian Journal of Gastroenterology, p. 184-192, 2020.

Article in journal

DOI for Diagnostic accuracy of a quantitative faecal immunochemical test vs. symptoms suspected for colorectal cancer in patients referred for colonoscopy Download full text (pdf) of Diagnostic accuracy of a quantitative faecal immunochemical test vs. symptoms suspected for colorectal cancer in patients referred for colonoscopy

Deep Remission at 1 Year Prevents Progression of Early Crohn's Disease

Ungaro, Ryan C.; Yzet, Clara; Bossuyt, Peter; Baert, Filip J. et al.

Part of Gastroenterology, p. 139-147, 2020.

Article in journal

DOI for Deep Remission at 1 Year Prevents Progression of Early Crohn's Disease

Vessby, Johan

Studies of ulcerative colitis with concomitant primary sclerosing cholangitis: Beyond the clinical phenotype

Doctoral thesis, comprehensive summary

Download full text (pdf) of Vessby, Johan

Utility of animal gastrointestinal motility and transit models in functional gastrointestinal disorders

Al-Saffar, Ahmad; Takemi, Shota; Saaed, Hiwa K.; Sakata, Ichiro et al.

Part of Baillière's Best Practice & Research, 2019.

Article, review/survey

DOI for Utility of animal gastrointestinal motility and transit models in functional gastrointestinal disorders

Al-Saffar, Anas Kh.

Gastrointestinal Permeability and Motility in Inflammatory Bowel Disease

Doctoral thesis, comprehensive summary

Download full text (pdf) of Al-Saffar, Anas Kh.

Prognostic significance of faecal eosinophil granule proteins in inflammatory bowel disease

Amcoff, Karin; Cao, Yang; Zhulina, Yaroslava; Lampinen, Maria et al.

Part of Scandinavian Journal of Gastroenterology, p. 1237-1244, 2019.

Article in journal

DOI for Prognostic significance of faecal eosinophil granule proteins in inflammatory bowel disease Download full text (pdf) of Prognostic significance of faecal eosinophil granule proteins in inflammatory bowel disease

Therapeutic potential of an anaerobic cultured human intestinal microbiota, ACHIM, for treatment of IBS

Benno, P.; Norin, E.; Midtvedt, T.; Hellström, Per M.

Part of Baillière's Best Practice & Research, 2019.

Article, review/survey

DOI for Therapeutic potential of an anaerobic cultured human intestinal microbiota, ACHIM, for treatment of IBS

Towards improved control of inflammatory bowel disease

Eberhardson, Michael; Hedin, Charlotte R. H.; Carlson, Marie; Tarnawski, Laura et al.

Part of Scandinavian Journal of Immunology, 2019.

Article, review/survey

DOI for Towards improved control of inflammatory bowel disease